Antimicrobial-induced Electrolyte and Acid-Base Disturbances

نویسنده

  • Yang Wook Kim
چکیده

Antimicrobials are one of the most widely prescribed classes of therapeutic agents. Although adverse effects of antimicrobials are generally minimal and reversible, serious sequelae can sometimes remain, such as unusual forms of renal failure, acid base disturbance and electrolyte abnormalities. Many antimicrobials, especially vancomycin or aminoglycosides, are associated with development of acute renal failure caused by acute tubular necrosis, allergic acute interstitial nephritis, or vasculitis. Besides, some antimicrobial agents can cause serious fluid and electrolyte imbalance. To prevent these serious consequences, early recognition and correction of their harmful renal and electrolyte effects are required.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Acid-base and electrolyte abnormalities in patients with acute leukemia.

Disturbances of acid-base balance and electrolyte abnormalities are commonly seen in patients with acute leukemia. Our study aimed at illuminating the probable pathogenetic mechanisms responsible for these disturbances in patients with acute leukemia admitted to our hospital. We studied 66 patients (24 men and 44 women) aged between 17 and 87 years old on their admission and prior to any therap...

متن کامل

Electrolyte and acid-base disturbances in critically ill patients: a retrospective and propensity-matched study

Background: Electrolyte and acid-base disturbances are common in critically ill patients. Their relationship with hospital mortality has not been clearly clarified. Methods: A retrospective propensity score matched analysis was used to evaluate the effects of electrolyte and acid-base disturbances on hospital mortality in critically ill patients from 2014 to 2015 in our hospital. Multiple logis...

متن کامل

Severe metabolic acidosis in a patient with an extreme hyperglycaemic hyperosmolar state: how to manage?

Severe acid-base disorders combined with electrolyte disturbances are of ten seen in patients with hyperosmolar hyperglycaemic state (HHS) or diabetic ketoacidosis (DKA). Acid-base disorders and electrolyte disturbances are tightly connected [1]. The aims of this clinical lesson are (i) to give insight in the relation between hyperglycemia, acid-base disturbances and electrolyte homeostasis, (i...

متن کامل

Acid-base and electrolyte status in carp (Cyprinus carpio) exposed to low environmental pH.

Carp (Cyprinus carpio) were exposed to environmental water pH (pHw) step changes from 7.4 to 5.1, 5.1 to 4.0 and 4.0 to 3.5 pH, PCO2, PO2 and lactate in dorsal aortic blood, [Na+], [K+] and [Cl-] in dorsal aortic plasma, base loss, and ammonia excretion were determined as a function of time after each pHw step change. At pHw 5.1 the measured blood acid-base and electrolyte parameters remained e...

متن کامل

Electrolyte and Acid-Base Disturbances Associated with Non-Steroidal Anti-Inflammatory Drugs

Inhibition of renal prostaglandin synthesis by non-steroidal anti-inflammatory drugs (NSAIDs) causes various electrolyte and acid-base disturbances including sodium retention (edema, hypertension), hyponatremia, hyperkalemia, and decreased renal function. Decreased sodium excretion can result in weight gain, peripheral edema, attenuation of the effects of antihypertensive agents, and rarely agg...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 5  شماره 

صفحات  -

تاریخ انتشار 2007